Biotech Innovations and Entrepreneurship: Insights from Jay Batchu D’18, TH’20, TH’21

On January 16, 2024, Jay Batchu D’18, TH’20, TH’21, graced the Magnuson Center at Dartmouth College with his presence, sharing invaluable insights on entrepreneurship and biotechnology with eager students. Batchu, a senior analyst and entrepreneur in residence at Xontogeny – a company dedicated to accelerating and investing in life science technologies – provided a captivating exploration of the latest trends, technologies, and advice for those seeking careers in entrepreneurship.

Xontogeny: Propelling Life Science Innovations


Batchu elaborated on Xontogeny’s dual role as an accelerator and venture investor in the biotech industry. Their accelerator program nurtures first-time and technical founders, providing partnership positions and initial funding. Additionally, the Perceptive Xontogeny Venture Fund serves as a second funding vehicle, exclusively focused on life sciences and healthcare.

Stealth Biotech Startup: Revolutionizing Antibody Development


Batchu offered a tantalizing glimpse into his own biotech startup, currently operating in stealth mode. The company, backed by seed funding from Xontogeny, is dedicated to developing bio-better antibodies using their proprietary conjugation technology. By modifying reference antibodies with specific modifiers, they aim to enhance antibody properties and unlock their full therapeutic potential.

Career Highlights and Notable Projects


Batchu’s diverse career in biotech and medtech boasts an impressive portfolio of projects. He recounted his research in cell therapy, engineered antibodies, enzymes, nanoparticle delivery systems, and urinary microbials with enthusiasm. However, it was his current work on antibody modification that elicited his greatest pride, as he believes it holds immense promise for therapeutic advancements.

COVID-19 Pandemic: A Catalyst for Biomedical Innovations


Batchu delved into the transformative impact of the COVID-19 pandemic on biomedical innovations. He noted how the pandemic accelerated the adoption of virtual fundraising and pitching, expanding the pool of potential investors for biotech companies. Additionally, the success of lipid nanoparticle approaches for vaccines revived interest in nanoparticles, which had previously faced skepticism. The pandemic also highlighted the need for more resilient and secure supply chains in the biotech sector.

Emerging Technologies in Biomedicine


Batchu identified antibody drug conjugates (ADCs) and cell therapies as exciting and promising areas in biomedicine. He emphasized the continued significance of antibodies, with new versions and applications emerging. Cell therapies, which involve treating diseases using cells, are also gaining traction and attracting significant interest. Batchu expressed his belief in the continuous emergence of innovative technologies in the field, driven by a healthy innovation environment.

Dartmouth Experience: A Foundation for Entrepreneurial Success


Batchu acknowledged the profound influence of his time at Dartmouth in shaping his entrepreneurial journey. He fondly recalled his involvement in projects such as DEN Associates (now the Magnuson Student Leadership Board) and TuckLab, which provided invaluable opportunities to develop essential skills in pitching, networking, communication, and experimentation. Batchu also expressed his gratitude for the support and mentorship he received from the Dartmouth Alumni network, particularly in the entrepreneurial and investor-oriented community.

Advice for Aspiring Biotech Entrepreneurs


Batchu generously shared valuable advice for students interested in pursuing entrepreneurship, particularly in the field of biomedicine. He stressed the importance of staying informed by reading research articles, conducting research with professors, and attending conferences. For those seeking professional entry into biotech, he recommended considering pursuing a graduate degree, such as a master’s or PhD. Batchu encouraged students to embrace entrepreneurship, emphasizing its rewarding and engrossing nature. He advised them to take advantage of the resources available at Dartmouth and to pursue their entrepreneurial aspirations with passion and determination.

Conclusion: Embracing the Future of Biotech


Jay Batchu’s visit to Dartmouth College provided students with an inspiring glimpse into the world of biotech innovations and entrepreneurship. His insights shed light on the latest trends, emerging technologies, and the impact of the COVID-19 pandemic on the field. Batchu’s own entrepreneurial journey and the work of his stealth biotech startup exemplify the transformative potential of biotechnology. His advice for aspiring entrepreneurs serves as a valuable guide for students seeking to make a meaningful impact in the world of biomedicine. As the industry continues to evolve, Batchu’s passion and expertise serve as a beacon of inspiration for the next generation of biotech entrepreneurs.